US
Adult Stem Cell Findings Re-Ignite Debate Over Embryos
By Patrick Goodenough
CNSNews.com Pacific Rim Bureau Chief
June 21, 2002
Pacific Rim
Bureau (CNSNews.com) - The publication of U.S. research highlighting
the evidently massive potential of "adult" stem cells has
breathed new life into an ethical debate in Australia, just days before
the introduction of legislation that would allow destructive research
on human embryos.
Ethics and
pro-life campaigners Friday welcomed the research, which has prompted
some government lawmakers to renew efforts for a total ban on research
that destroys embryos.
The new data
may also re-ignite the debate in the United States, where the Senate
is considering whether to allow the cloning of human embryos for research
purposes.
Many scientists
and bio-technology engineers believe stem cells harvested from embryos
- which are destroyed in the process - will one day help treat diseases
such as diabetes and Parkinson's.
Pro-lifers
have long argued that adult stem cells, from sources such as umbilical
cords or bone marrow, offer an ethical alternative, and they point to
a growing stack of evidence of their efficacy.
The latest
study comes from the University of Minnesota, where researchers have
found that adult stem cells from bone marrow can turn into virtually
every single tissue in the body, from muscle to nerve to blood.
The study,
published Thursday in the journal "Nature," suggests that
these multipotent adult progenitor cells (MAPC) found in the bone marrow
of rats and could be just as versatile as those from embryos - a point
long disputed by proponents of embryonic research.
Moreover,
Prof. Catherine Verfaillie said she and her colleagues had not found
any evidence so far that the adult cells could grow into tumors, which
is a concern with embryonic stem cells.
News of Thursday's
report, which confirmed findings first reported last January, prompted
some scientists in Australia and Britain to caution that this shouldn't
mean research on embryos should stop. Rather, work should continue on
both types of cells, they said.
Conscience
vote
In Australia,
the debate over stem cell research has pitted religious, ethics and
pro-life campaigners against an influential and successful biotechnology
industry.
After weeks
of lobbying from both sides, and under pressure from state governments
that threatened to defy any federal ban, Prime Minister John Howard
in early April decided to allow research on embryos, which as of that
date had already been created during in-vitro fertilization (IVF) treatment.
The decision
was followed in late May by an allocation of $24.6 million in federal
funding to a new center for stem cell research, headed by a top scientist
who supports research on human embryos, including embryos cloned in
a lab.
Legislation
allowing the research is due to be introduced in the federal parliament
next week, with the major parties having agreed to allow their members
a conscience vote.
A petition
is now circulating among lawmakers in the Liberal Party-led coalition
urging members to vote for a total ban.
On opponent,
Liberal lawmaker Chris Pyne said the U.S. research showed you could
have "good science without dubious experimentation on embryos."
At least
three cabinet ministers have indicated support for a ban.
Armed with
the University of Minnesota study, Australian opponents of embryonic
stem cell research Friday called variously for lawmakers to vote in
favor of a total ban, or for the legislation to be deferred pending
the ongoing research into adult cells.
"These
fantastic findings indicate that adult stem cells are as versatile as
embryo stem cells and that, unlike embryo stem cells, they will not
cause cancer," said Dr. Amin Abboud, director of Australasian Bioethics
Information.
Abboud, who
lectures in medical ethics at a Sydney university, said the study showed
that "we can use the resources of the human body to cure itself
without having to kill embryos."
Abboud also
accused embryonic stem cell advocates of keeping "under wraps"
the propensity of embryonic cells to produce cancerous tumors called
teratomas.
Research
at the Harvard Medical School published last January suggested that
embryonic stem cells from rats could change into cells that produce
dopamine, a chemical needed by Parkinson's patients.
But in 20
percent of the rats used in the experiment, the cells reportedly instead
formed a teratoma. In humans, such a result would be devastating, according
to experts, as many teratomas are inoperable.
Profit agenda
Another group
that has lobbied against embryonic research is the Australian Family
Association.
AFA national
vice president Bill Muehlenberg said Friday many of those advocating
the controversial research were motivated by the promise of financial
gain.
"Science
has given way to other agendas of Big Biotech, and many political leaders
are being duped in the process," he said.
"It
is time for real science to set the agenda, not the profit-driven motives
of Big Biotech and the pharmaceuticals."
Both Muehlenberg
and Abboud argued that while the ability of adult stem cells to treat
diseases was repeatedly being tested and proven, the potential of embryonic
cells to do likewise remained unknown.
The AFA sees
the way the debate has gone in Australia as a sign of the decline of
ethics in Western societies.
"When
we fought the battle on IVF two decades ago, we warned that this was
the thin edge of the wedge," Muehlenberg said. "It seems that
we have not seen the last of the moral erosion enfolding before our
eyes."
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